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Semintra for cats



Active ingredient



Kidney / Blood Pressure

What is Semintra?

Semintra is a brand name for a drug with the active ingredient Telmisartan. It is an Angiotensin II Receptor Blocker (ARB), a type of drug which widens blood vessels. This reduces high blood pressure and slows the progression of chronic kidney disease in cats.

What does Semintra do?

Telmisartan, the active ingredient in Semintra, is known as an Angiotensin II Receptor Blocker. This means it specifically targets and blocks the action of Angiotensin II, a substance in the body that narrows blood vessels and increases blood pressure.

By blocking the effects of Angiotensin II, Semintra helps relax and widen the blood vessels. This effectively lowers blood pressure, which is particularly beneficial for cats with high blood pressure (hypertension). 

Semintra also has beneficial effects for cats with chronic kidney disease (CKD).  In cats with CKD, the blood pressure in the kidneys is abnormally high. This causes proteins to leak into the urine (proteinuria), which worsens CKD. By reducing hypertension and proteinuria, Semintra reduces further damage to the kidneys and slows the progression of CKD.

What is Semintra for?

Semintra is used for the following conditions in cats:

  • High blood pressure (hypertension): Commonly prescribed for cats with hypertension due to kidney disease, abnormally high thyroid levels (hyperthyroidism), etc.
  • Protein in the urine (proteinuria): Proteinuria associated with Chronic Kidney Disease (CKD) 

What are the possible side effects with Semintra?

While generally well-tolerated, Semintra may have side effects, including:

  • Mild vomiting and diarrhoea: These usually happen in the first week or two and are often short-lived.
  • Change in appetite and weight: Some pets may experience a  loss of interest in food, leading to weight loss.
  • Weakness: Pets may have reduced activity if there is a marked drop in blood pressure.
  • Increased liver enzymes:  Elevated liver enzymes may indicate liver issues. However, this is a rare side effect and liver values usually normalise a few days after Semintra is stopped. 
  • Low red blood cell count (anaemia): Mild anaemia – a rare side effect- may occur in cats on Semintra.

Once your veterinarian starts your cat on Semintra, follow-up vet appointments and bloodwork are recommended to monitor your cat’s response to Semintra.
Remember, if you ever notice anything unusual about your cat after they start taking Semintra, even if it’s not on this list, always play it safe and give your vet a call. They’re there to help ensure your furry friend stays happy and healthy!

How to give Semintra safely

1. Follow vet instructions: Always use Semintra exactly as your vet has prescribed. This includes the right dose and frequency. Never adjust the dose on your own, even if your cat seems to be feeling better or worse. If you aren’t sure of the dose prescribed, please call your vet to confirm.

2. Administer directly into the mouth: Semintra is best given without food, and should not be mixed into food. Consult your veterinarian if your cat refuses to take Semintra without food.

3. Check with your vet if giving anything else: Your vet should be aware of other drugs your pet is on, but it’s always worth double-checking in case there’s been a miscommunication somewhere. If your cat is on supplements or non-prescription treatments you should also tell your vet when they prescribe Semintra, as they may not be suitable to be given together.

4. Storage and handling: Store Semintra according to the instructions on the packaging, usually in a cool (below 25°C) and dry place. Make sure it’s out of reach of children and other pets. Wash hands after use. Pregnant women should not handle Semintra, as similar drugs can harm foetuses. 

5. Report any accidental overdose to your vet immediately: If you have mistakenly given too much Semintra, report it to your vet as soon as you realise the error. They may recommend blood tests, intravenous fluids, or monitoring, depending on the severity of the overdose.

Semintra FAQs

How effective is Semintra for cats?

Studies show that Semintra is effective for cats. In a field study of cats mainly above 11 years old with kidney disease, Semintra lowered urine protein levels within the first seven days of starting treatment.

Another study was done on cats with high blood pressure and an average age of 13 years. After 28 days of treatment, the blood pressures of the cats on Semintra had improved compared to those on a placebo treatment.

Does Semintra make cats drowsy?

Semintra can make cats drowsy, as lethargy is a possible side effect of Semintra. If you notice your cat has become drowsy, you should contact your vet for advice.

Does Semintra need to be given with food?

Semintra is best given without food.  Consult your vet if your cat refuses to take Semintra without food. Semintra can be placed on top of a small amount of food if really needed, but should not be mixed into food – so do discuss this with your vet before you proceed.

Is Semintra safe for cats?

Semintra is safe for most cats. However, pregnant or lactating cats should not be given Semintra. Furthermore, the safety of Semintra has not been evaluated in cats below 9 months old. As each cat’s health status is unique, your vet is the best person to determine whether your cat is a suitable candidate for Semintra.

Semintra Datasheet

All drugs have a manufacturer’s datasheet, which gives information about the drug’s use and possible side effects. There is usually one in your Semintra box, but if you have lost it you can click on the button below to be taken on an online version.

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