Cimalgex for dogs



Active ingredient



Pain relief / anti-inflammatory

What is Cimalgex?

Cimalgex is the trade name of the drug named cimicoxib. It is a type of anti-inflammatory called a non-steroidal anti-inflammatory drug and is mainly used to treat the pain associated with arthritis. Rather than just blocking the signs of pain, Cimalgex also reduces inflammation, thereby treating the cause of the pain too.

What does Cimalgex do?

Cimalgex, with the active ingredient cimicoxib, is a nonsteroidal anti-inflammatory drug (NSAID) designed for dogs to alleviate pain and inflammation, particularly associated with osteoarthritis, but also after surgical procedures. Here’s a straightforward overview for pet owners:
How Cimalgex Works:

  • Active Ingredient: Cimalgex contains the active ingredient cimicoxib.
  • Mode of Action: Cimalgex works by inhibiting enzymes known as cyclooxygenase-2 (COX-2), which are involved in the production of inflammatory substances. By reducing inflammation, Cimalgex helps manage pain associated with conditions like osteoarthritis.

What is Cimalgex for?

  • Osteoarthritis Relief: Cimalgex is primarily prescribed to dogs with osteoarthritis to improve mobility by reducing pain and inflammation in the joints.
  • Pain Management: It is used for the short-term or long-term management of pain associated with various conditions and injuries.
  • Peri and postoperative Pain: In some cases, Cimalgex may be used just before and following surgery to manage pain.

Always follow the veterinarian’s recommendations for the correct dosage based on your dog’s specific needs. Regular veterinary check-ups are important to monitor your dog’s response to Cimalgex and make any necessary adjustments. If you notice any unusual or persistent symptoms in your dog, contact your veterinarian for guidance.

What are the possible side effects with Cimalgex?

  • Gastrointestinal Upset: Some dogs may experience gastrointestinal upset, including vomiting or diarrhoea. This is often temporary and may improve with continued use. Rarely, the gastrointestinal side effects are more severe, and you may notice blood in your dog’s stools – if this is the case, contact your vet right away as it could indicate ulceration of the gastrointestinal tract.
  • Decreased Appetite: Cimalgex can cause a temporary decrease in appetite in some dogs.
  • Changes in Behavior: Rarely, dogs may exhibit changes in behaviour, such as lethargy or increased irritability.
  • Renal Effects: NSAIDs, including Cimalgex, can affect kidney function. It’s essential to monitor for signs of increased thirst, changes in urination, or lethargy, which may indicate kidney issues.
  • Liver Effects: While rare, elevated liver enzymes may occur. Regular monitoring may be recommended.
  • Allergic Reactions: In very rare cases, dogs may experience an allergic reaction, characterised by swelling, itching, or difficulty breathing.

Remember, not all pets will experience these side effects, and the benefits of using Cimalgex often outweigh the risks, especially in pets with serious health conditions. However, if you notice any concerning symptoms or changes in your pet’s behaviour or health while they are taking Cimalgex, it’s important to contact your veterinarian immediately. They can provide guidance and adjust the treatment plan if necessary to ensure your pet’s safety and well-being.

Which pets is Cimalgex not suitable for?

  • Cimalgex should only be used in dogs, it is not licensed for cats. However, vets can use medications off-label based on experience.
  • Cimalgex is not suitable for dogs under 10 weeks old, and its safety in dogs under 6 months old has not been confirmed; therefore it should only be used in these dogs following direct veterinary advice.
  • Cimalgex should not be used in breeding dogs or those who are pregnant or lactating. It can affect fertility as well as foetal development.
  • Cimalgex may not be suitable for dogs who won’t take tablets. However, the tablets are chewable and intended to be palatable. They can also be given with food which may make them easier to give.
  • Cimalgex shouldn’t be used in dogs who are allergic to the active ingredient.
  • Cimalgex shouldn’t be used alongside other non-steroidal anti-inflammatory drugs or steroid-based anti-inflammatories.
  • Cimalgex may not be safe for use in dogs with kidney, liver, or heart problems; therefore, always follow your vet’s advice.

How to give Cimalgex safely

  • Follow vet instructions: Always use Cimalgex exactly as your vet has prescribed. This includes the right dose and frequency. Never adjust the dose on your own, even if your dog seems to be feeling better or worse. If you aren’t sure of the dose prescribed, please call your vet to confirm.
  • Be consistent with food: Cimalgex can be given with or without food, but it’s best to be consistent every time as to whether you give it with food.
  • Check with your vet if giving anything else: Your vet should be aware of other drugs your pet is on, but it’s always worth double-checking in case there’s been a miscommunication somewhere. If your dog is on supplements or non-prescription treatments you should also tell your vet when they prescribe Cimalgex, as they may not be suitable to be given together.
  • Storage and Handling: Store Cimalgex according to the instructions on the label, usually in a cool and dry place. Make sure it’s out of reach of children and other pets.
  • Report any accidental overdose to your vet immediately: If you have mistakenly given too much Cimalgex, report it to your vet as soon as you realise the error. They may recommend blood tests, intravenous fluids, or monitoring, depending on the severity of the overdose.
  • Wash your hands after handling: Cimalgex can cause skin sensitivity. Consider wearing gloves to handle the tablet or wash your hands immediately after handling. Contact a human healthcare professional if you are concerned.

Cimalgex FAQs

How long can a dog take Cimalgex?

A dog can take Cimalgex from two hours before surgery to seven days after surgery, if needed. For the treatment of arthritis a dog can take Cimalgex for up to six months. If longer treatment is required then regular blood tests should be performed to check liver and kidney function.

Can I give Cimalgex to my pregnant or nursing dog?

It’s important not to give Cimalgex to a pregnant or nursing dog. It should also be avoided in any dog intended for breeding. This is because it can affect fertility and foetal development.

Can Cimalgex be used in puppies or senior dogs?

Cimalgex should not be used in puppies. It is ideally suitable for dogs aged six months or more; however, in some cases it can be safely used between 10 weeks and six months of age. It’s important to check a senior dog’s kidney, liver, and heart health before treating them with Cimalgex.

What should I do if I miss a dose of Cimalgex?

Cimalgex should be given at the same time every day. If a dose is missed you can still give the tablet, but you shouldn’t give another tablet for 24 hours, so continue giving the medication at the new time every day. If you’d rather keep the dose time the same, wait until the following day and monitor your dog for signs of pain.

Can my dog develop a tolerance to Cimalgex over time?

Your dog shouldn’t develop a tolerance to Cimalgex, and it should remain effective. However, since it is often used for arthritis, as the condition gets worse over time additional medication could be needed to keep your dog comfortable.

Are there specific signs that indicate Cimalgex is working for my dog’s osteoarthritis?

If Cimalgex is working for your dog’s osteoarthritis, you might notice them being more active. They may be able to get up more easily, run and play more, and any limping may resolve.

Cimalgex Datasheet

All drugs have a manufacturer’s datasheet, which gives information about the drug’s use and possible side effects. There is usually one in your Cimalgex box, but if you have lost it you can click on the button below to be taken on an online version.

Courses related to Cimalgex

Please note that the information contained herein is provided for informational purposes only. Although it has been written by a vet, we cannot consider the individual nature of your pet’s problems so it does not constitute veterinary advice. If you have questions about your pet’s medication or their health you should contact a vet, who will be able to help.